Here we report the first high-throughput and candidate sequence analyses of DNA methylation to investigate discordance for autoimmune disease in twins.

• 目前，许多研究认为表观遗传修饰会影响表型以及疾病的发生率。而且，诸如饮食或接触化学品等环境因素也能影响基因的表观遗传特征。