HIF-dependent suicidal gene therapy system Ad-5HRE/hCMVmp-BCD/5-FC can be used as a powerful therapeutic method for renal cell carcinoma.

• HIF依赖性表达的Ad-5HRE/hCM-Vmp-BCD/5-FC自杀基因系统可显著抑制肾细胞癌生长,具有良好的临床应用前景。