HBV integrating into hepatocellular chromosome of the patients with chronic hepatitis B not only can lead to a result of hereditary diseases, bur also is a high risk factor for liver cancer.

• 慢性乙型肝炎患者肝细胞染色体上存在整合型HBV，使HBV感染可能发展成为一种遗传性传染性疾病，并成为肝癌高发的重要危险因素。