HATU as the coupling reagent; TFA, p-methyl phenol, EDT and H2O (97:0.25:0.25:2.5) as the cleavage condition, the yield of thymopentin was 79.68% and the purity was 80.36% under 2 equiv.

• 反应结果胸腺五肽纯度达80.；36%25；收率达79