Furthermore, it can present a ra tional basis for treatment of intensification in the patients who did not respon d to first-line DLI treatment.

• 结论 :嵌合体检测可指导DLI的实施时机 ,预测DLI的临床疗效 ,而且对首次DLI治疗无效的患者的后继强化治疗提供重要的参考依据。