For example, when a patient develops lamivudine resistance, you have to add adefovir or maybe tenofovir, to control the resistance, or might also use entecavir.

• 例如，当患者出现拉米夫定耐药后，就需要加上阿德福韦酯或者替诺福韦，或甚至使用恩替卡韦来控制耐药。