Folate may interfere with the efficacy of methotrexate, and antioxidants may preent the cellular oxidatie damage to cancer cells that are required for efficacy of radiotherapy and chemotherapy.

• 叶酸可能干扰氨甲喋呤的疗效，抗氧化剂可能会阻断放化疗效果所必需的对癌细胞的细胞氧化损伤。