Experimental data indicated that doxepin gel had significant inhibitory effects on edema in the ears of mice induced by xylene and swollen feet induced by albumen injection, also inhibitory inflammation animal by DNCB.

• 对小鼠二甲苯致耳部水肿、鼠蛋清引起的足跖肿胀的炎性模型亦呈现明显的抗炎作用，并能抑制2，4-二硝基氯苯诱发的炎症反应。