Except for the CDP-Choline pathway, it also has a special PC synthesis pathway in mammals, in which phosphatidylethanolamine N-methyltransferase catalyzes phosphatidylethanolamine to form PC.

• 在哺乳动物肝脏中，除了CDP-胆碱通路(又称Kennedy通路)外，还存在一条特有的PC合成通路，即磷脂酰乙醇胺N-甲基转移酶(phosphatidylethanolamineN-methyltransferase，PEMT)催化磷脂酰乙醇胺(phosphorylethanolamine，PE)甲基化生成PC的通路。