Endothelin can affect the contractile properties of cardiacmyocyte, stimulate myocyte growth and myofibrillogenesis, and increase resistance to apoptosis by intracellular signaling pathways.

• 内皮素通过多种心肌细胞内信号途径调节心肌细胞的收缩特性,刺激心肌细胞生长和肌原纤维的产生、抗凋亡等作用。