Eligible trials were randomised controlled trials enrolling mechanically entilated adults that compared the effects of daily oral application of antibiotics or antiseptics with no prophylaxis.

• 采用随机对照研究方法，将机械通气患者分为两组，实验组是每天都进行口服抗生素或者消毒液组，对照组则未进行口腔护理。