Each component eluted from HPLC can be deposited in an area of 0.01 mm 2. A detection limit of less than 1 ng is possible for on line measurements even when volatile buffers are used.

• 应用CFN技术，能显著减小LC组分的析出面积（约0?01mm2），在挥发性缓冲剂存在下，其检测限低于1ng。