During the cardiac ischemia/reperfusion or cardenolide intoxication, the inflow Ca(superscript 2+) through NCX reverse mode induce calcium overload and arrhythmia.

• 缺血／再灌注或强心苷中毒时会使细胞外的钙通进钠钙交换体的反向模式内流，造成内钙超载，导致心律失常。