Due to the improvement of locoregional control in advanced OSCC by the advancement of treatment modality, more patients are faced with the risk of developing distant metastases.

• 现今由于治疗方式的进步，在晚期口腔鳞状上皮癌患者，虽然其局部复发情形有显著的控制，但有愈来愈多的患者面临了远端转移的情形。