Detection of clonal IgH gene rearrangement by seminested PCR provides a simplified, highly specific and sentitive method for detecting MRD of B lineage neoplasma.

• 半巢式PCR检测克隆性IgH基因重排，方法简便，敏感性和特异性高，可用于B细胞恶性肿瘤MRD检测