Daunorubicin was linked covalently to the purified M cAb1A 1 via a dextran bridge. M cAb1A 1-PAD-DNR conjugate retained substantially the original immunological and pharmacological activities.

• 用葡聚糖作中间体将M_cAb_1A_1与柔红霉素（DNR）偶联，制备的免疫偶合物仍保持较好的抗体活性及药物活性。