Cyclosporin A was encapsulated with empty liposomes and the techniques was optimized with orthogonal design.The encapsulation ratio of cyclosporin A was determined by HPLC.

• 采用空白脂质体法制备环孢素A脂质体喷雾凝胶,用正交设计筛选制备工艺,高效液相色谱法测定包封率;