Currently, most of the NR2B antagonists known are structurally related to ifenprodil, and some belongs to the types of amides, amidines and aminoquinolines.

• 目前,已报道的NR2B亚型阻滞剂的结构类型绝大多数仍为艾芬地尔发展而来的哌啶衍生物,另外还有酰胺、脒、氨基喹啉等结构类型;