Conclusions : CXCR3 chemokines and CCL5 are increased in sputum from COPD patients compared with nonsmokers, and may be important in COPD pathogenesis.

• 结论：与不吸烟者相比，COPD患者诱导痰中同CXCR3结合的趋化因子和CCL5浓度增加。提示在COPD发病机制中，这些趋化因子可能发挥重要作用。