Conclusion The results demonstrate that the formation of an ion pair between KP and amine may be responsible for the enhanced skin permeation of KP using amine-EI system.

• 结论：结果表明，EI系统中有机胺对KP的经皮渗透有促进作用。这种渗透促进作用可能依赖于KP与胺之间所形成的离子对组成。