Conclusion The glucoprotein part of AFP is remarkably different between HCC and benign hepatic disease by micro-column affinity chromatography assay.AFP-L3 is the specific marker for diagnosing HCC.

• 结论使用微柱亲和层析法分析肝癌AFP其糖蛋白部分与良性肝病明显不同，AFP-L3是诊断肝癌特异标志物。