Conclusion The concentrations of cefoperazone sodium, chloromycetin, ciprofloxacin lactate and gentamycin sulfate showed significant influence on the coagulation time and detection rate of fibrinogen in plasma.

• 结论头孢哌酮钠、氯霉素、乳酸环丙沙星、硫酸庆大霉素等抗菌素及其浓度变化对血浆中纤维蛋白原的凝固时间和检出率有显著影响。