Conclusion The ability of PT to induce specific antibody is conformation dependent of intact PT, and antibody induction domains are located dominantly in S1 subunit of intact PT.

• 结论百日咳毒素诱导产生特异性抗体的能力依赖于聚合体的空间构型，而且其主要抗原决定簇位于聚合体的S1亚基上。