Conclusion Hirudin is able to inhibit the occurrence and development of traumatic brain edema;it can reduce complication and improve therapeutic effects if hirudin is used at the early stage.

• 结论水蛭素可抑制脑挫裂伤后脑水肿的发生和发展,早期应用水蛭素可减轻脑水肿,降低并发症,提高疗效。