Conclusion Ads neutralizing antibody is prevalent in the population of Guangzhou, suggesting the necessity of developing other serotype adenovectors for better vaccination and therapeutic effects.

• 结论5型腺病毒在广州人群中具有一定的免疫程度，结合中和实验结果来应用该种病毒载体并同时开发其他血清型的腺病毒载体很有必要。