Compared with AKA negative ones,AKA positive RA patients developed more severe disease activity based on hands deformity,TJC,SJC,degree of joint erosion and DAS28. Conclusions(1)Compared with RF,AKA shows higher disease specificity in RA patients.

• RA组AKA阳性、阴性者各指标除手关节畸形、压痛关节数、肿胀关节数、关节侵蚀程度差异有统计学意义(均P<0.；05)外；余均P>0