Calix[4]arenes bearing ester pendants in the lower rim were prepared by a convenient method using the more economical and less toxic ethyl chloroacetate/alkali metal iodide as an alkylating reagent.

• 采用更为经济和毒性较小的氯乙酸乙酯-碱金属碘化物体系作烷基化试剂；方便地制得了下缘带有酯基基团的杯[4]芳烃.