CRF family peptides, which elicit their effects through G-protein-coupled receptors known as CRF1 receptor and CRF2 receptor, are capable of strong anorectic and thermogenic effects.

• CRF家族肽与G蛋白偶联受体CRF1R或者CRF2R结合能够产生强烈的厌食及产热作用。