Bz-Arg-Gly-Asp-(NH2)2 , a precursor tripeptide of RGD was synthesized by a combination of chemical and enzymatic methods in this study.

• 经过反复尝试，终于探索出一条酶法和化学法结合合成RGD三肽的路线。我们利用一种新颖的化学法和酶法相结合的策略成功地合成了RGD 前体三肽Bz-Arg-Gly-Asp-(NH2)2。