By the method of AM1, quantum chemistry indexes of 16 compounds of quinoline, 1,8-naphthyridine and pyrido(2,3-C)pyridazine analogues were calculated and 4 QSAR equations were obtained.

• 利用量子化学半经验分子轨道AM1方法对喹啉、萘啶、吡啶[2,3-C]哒嗪环系的系列化合物进行了定量构效关系研究，建立了很好的QSAR方程。