Bothe noxious stimulus and acupuncture enhance the expression of PPE mRNA with regional defference and the expression of PPE mRNA may be modulated by the Fos protein.

• 针刺和痛刺激均能激活内阿片肽基因表达，但程度上有差异，而刺激组所表达的共存变化可能表明Fos参与EnkmRNA等基因表达