Both SP and CGRP belong to neuropeptide,it has been reported there is SP and CGRP synthesis in the lesions of PN.

• 目 的： 结节性痒疹是和神经精神因素相关的疾病，SP和CGRP都属于神经多肽，已经发现在结节性痒疹皮损中存在SP和CGRP。