Between codon 40 and 41, C was inserted. SU-DHL-4 and SU-DHL-6 had bcl-2/JH fusion genes. The significance of gene conformational changes affected pathogenesis, development of malignant lymphoma cell lines was discussed.

• SU-DHL-4和SU-DHL-6有bcl-2/JH基因的重排,讨论了基因结构的变化在恶性淋巴瘤细胞系发生发展中的意义。