Balsalazide sodium was synthesized from 4-nitrobenzoic acid via chlorination, condensation, hydrogenation, diazotization, coupling and salt formation. The overall yield was 73.0%.

• 以对硝基苯甲酸为原料；经氯化、缩合、还原、重氮化、偶合、成盐等6步反应制得巴柳氮钠；总收率73.；0%25。