Background: Coxsackievirus A16 (CA16) and Enterovirus 71 (EV71) are two major etiological agents of hand, foot and mouth disease (HFMD) in children.

• 手足口病是儿童中常见的肠道病毒感染性疾病，柯萨奇病毒A组16型（CA16）和肠道病毒71型（EV71）是其主要病原。