BCG-CpG-DNA increased the anti-HBs neutralizing antibody level,promoted the production of antigen specific IgG2a,induced Th1 immune response,and partially reversed Th2 response.

• BCG-CpG-DNA能提高抗-HBs中和抗体水平,促进抗原特异性IgG2a的产生,诱导Th1型免疫应答,与铝佐剂协同作用能部分逆转Th2反应。