At light on phase, histamine contents in hypothalamus, thalamus and cortex were significantly lower in DPR-KO mice than in WT mice (P=0.0384, 0.0455 and 0.0179, respectively).

• 明时处死,DPR基因敲除型小鼠皮层、下丘脑及丘脑中的组胺含量明显低于野生型小鼠;