Arsenic can inhibit the expression of CTF gene, starting of gene transcript was blocked, so it can cause the expression of many of genes to be declined. This result may be ones of the mechanisms of arsenical genetic toxicity.

• 砷可抑制 CTF基因的表达 ,使基因转录的起始受阻 ,从而导致大部分基因表达水平下调 ,这可能就是砷遗传毒性的机理所在