Approximately 71.4% of the 28 cases of APL showed cardiac toxic reaction in different degree in the first week after As 2O 3 intravenous infusion in general dose, mainly expressing rapid heart rate or prolonged QT interval.

• 2 8例APL患者中 ,有 71 4%25的患者产生不同程度的心脏毒性反应 ,表现为心率加快和心电图上QT间期 (QTc)延长。