Antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC) are involved in the mechanisms underlying the efficiency of MAb against tumor.

• 单克隆抗体作用肿瘤细胞相应的分子靶点后,产生的生物学效应主要包括抗体依赖性细胞毒作用(antibody dependent cellular cytotoxicity,ADCC)和补体依赖性细胞毒作用(complement-dependent cytotoxicity,CDC)。