Animal model establishment80 male Sprague-Dawley SPF rats were selected, weighing 350~410g (12-14 w) (purchased from The Animal Facilities of Akita University, Japan). Rats were randomly divided into shock-reaming, reaming, shock and control groups.

• 选用雄性Sprague-Dawley SPF大鼠，体重350-410克(12-14周)80只(购自日本国秋田大学动物实验中心)，随机分为休克扩髓组、扩髓组、休克组及对照组。