An intramural venous leiomyosarcoma of the distal end of great saphenous vein is presented with initial symptom of a small painless nodule on the left lower leg of a 58 year-old male patient.

• 我们在此报告一个58岁男性病患，大隐静脉末端发生的静脉壁内平滑肌肉瘤，其最初临床表现为左小腿无痛性的小肿瘤。