Among 770 included patients, 724 and 718 were screened for intention to treat (ITT) and per-protocol population set (PPS) analysis, respectively.

• 纳入患者770例,随机化763例,剔除28例,脱落17例,最终进入意向治疗(ITT)分析724例,符合方案集分析(PPS)718例。