Although Botox has been used off-label for years in spasmodic dysphonia, there have been no long-term data on the effect of repeated injections on V-RQOL.

• 虽然保妥适在痉挛性发声困难方面，已被标签外使用多年，但此药在V-RQOL量表下，尚无重复注射效果的长期研究资料。