Aim The purpose of this study was to determine biochemical and morphological perspectives of myocardial collagen during reactive and reparative fibrosis in two kidney one clip renovascular hypertensive rats(2K1C RHT).

• 采用二肾一夹肾血管性高血压（2K1C－RHT）大鼠为模型，观察在反应性和修复性纤维化阶段心肌胶原形态和生化的改变。