After G418 selection, stable wt p53 transformants, TDN p53 transformants and control vector transformants (pNeo) were obtained.

• 经G418筛选获得稳定的整合了野生型 p5 3的克隆 (wide typep5 3 ,wt p5 3 )、突变型 p5 3克隆 (trans doninantnegativep5 3 ,TDNp5 3 )和空载体克隆 (pNeo)。