AUMC is the area under the first moment of the plasma concentration-time curve. For a drug with one-compartment distribution characteristics, MRT equals the reciprocal of the elimination rate constant.

• 其中AUMC是指一阶矩血浆浓度时间曲线下面积。对具有一室分布特征的药物来说,MRT等于消除速率常数的倒数。