AIM:To study the effect of bcr - abl gene antisense phosphorothioate oligonucleotides(Aspo) on K562 cell line and explore its significance in chronic myelogencous leukemia (CML) gene therapy.

• 目的：研究 bcr－abl融合基因硫代磷酸反义寡核苷酸（Aspo）对 K562细胞生长特性的影响，探讨其在慢性粒细胞白血病（CML）基因治疗中的意义。