A novel gas chromatographic method for the determination of lactic acid in serum and cerebrospinal fluid (CSF) of patients with mitochondrial encephalomyopathy has been developed.

• 血清和脑脊液样品经甲酯化处理,氯仿提取,氮气吹干,残留物用庚烷溶解后进样,用气相色谱法测定线粒体脑肌病患者血清和脑脊液中乳酸含量。