A method to direct-detect immunoreactions on surface of optical fiber by interference principle is introduced, whose thickness testing precision of bio-layer is up to angstrom grade.

• 提出了利用光学干涉原理在光纤传感器端面上直接测量生物免疫反应的方法 ,能够测试到纳米级厚度生物膜层的亚纳米级厚度增加量。